#potentially hot for nerds

Mid-twenties, Australian, fangirl.
Apparently I'm a cell biologist.
Posts I Like
Posts tagged "also"

katherinehcastles:

Extreme Dodgeball: Avengers Edition

(via grayjumper)

kayquimi:

scifigrl47:

darkmagyk:

Didn’t I watch a terrible children’s movie about this? Also, haven’t all of these couples broken up. 
Also, we all know its Nat and Bucky’s kid and Steve took responsibility for some stupid ass noble reason. 

Well, technically, they only say “Black Widow and Captain America” and Bucky has been Captain America for whole stretches of time.
So it could totally be Bucky just as written.

Even if Bucky’s not secretly the father…. THEY NAMED HIM JAMES. The heartwrenching backstory practically writes itself.

There have also been people using the Black Widow name other than Natasha. (Though I honestly don’t know whether they count. I am not a comics person shhhh don’t look at me.)

kayquimi:

scifigrl47:

darkmagyk:

Didn’t I watch a terrible children’s movie about this? Also, haven’t all of these couples broken up. 

Also, we all know its Nat and Bucky’s kid and Steve took responsibility for some stupid ass noble reason. 

Well, technically, they only say “Black Widow and Captain America” and Bucky has been Captain America for whole stretches of time.

So it could totally be Bucky just as written.

Even if Bucky’s not secretly the father…. THEY NAMED HIM JAMES. The heartwrenching backstory practically writes itself.

There have also been people using the Black Widow name other than Natasha. (Though I honestly don’t know whether they count. I am not a comics person shhhh don’t look at me.)

comicbookchic:

marvelentertainment:

Announcing the ULTIMATE Marvel gals’ fashion line from heruniverseofficial, with all your favorite Marvel characters on tops, tanks, dresses, cardigans, hoodies, skirts, leggings and more!

See them now right here: HerUniverse.com

Safe to say I’m getting the shield/hydra too and the cap cardigan

(via flux-capacitard)

joligirafeau:

sixpenceee:

Something strange is happening in Singapore today. 

On a busy street in Singapore, residents discovered a small doll leaning against a tree. The doll looked somewhat antique and had its eyes covered with a cloth. The cloth had some arabic text written on it. The doll’s backstory and the subsequent research hinted at the fact that the doll was possibly possessed.

In the words of the person who posted the pictures on Reddit, “The doll was found beside a busy street in Singapore. The Arabic word on the cloth is translated as ‘Bismillah’.

The ‘Bismillah’ maybe a blessing to keep the demon or jinn possessing it inside the doll at all times.

Stories from twitter revealed that the doll is possessed and has been moving around on its own when the original owner isn’t home. The owner binded the eyes and left it far away from home so it wouldn’t follow her back.

"Some say the doll can be heard talking when it’s left alone in a room and is found with its head turned in a different direction. It is said that it spoke in a Malay language and sound like an adult female.”

The original owner found that the only way to get rid of it and make sure it won’t come back is to cover its eyesight. The curse is rumored to have passed on to someone else who found it and untied the cloth unknowingly.

WHERE I GOT THIS INFORMATION FROM

I love stuff like this mmm

(via misandryad)

Novel buddies!

High-five! 

blue-author:

runnerjive:

thre3dprint:

Open Source Clothing.

Now I feel it imperative to reblog this, because the project seems to have hit a snag: The video they put up has been taken down because of claims of 3rd-party content, whatever whatever corporate lawyer stuff internet throttling stuff. That makes me think that Bennetton or one of the others whose stores were glimpsed in the background got their hooks in Vimeo.So I thought I’d tell you a yarn about how this thing works: You download the open-source plans for the machine. You build it. You download their open-souce clothing-maker program.You enter the desired measurements into the fields (the ones I remember from the video were arm and neck and chest measurements, so I’m sure they have waist and/or hips too)You print out your sweater, or hat, or scarf, or cardigan, or whatever it was that you selected. It takes an hour to print out the sweater, working off of the two yarn spools that you can see in the bottom right corner of this .gifThat’s it. Custom-fit, custom-color clothing in an hour, for the price of yarn. Can you see why one of the clothing companies targetted in the video might have felt threatened enough to force the video to come down?

I know if I sold overpriced manufactured clothes, I’d see this as a looming menace.

blue-author:

runnerjive:

thre3dprint:

Open Source Clothing.

Now I feel it imperative to reblog this, because the project seems to have hit a snag: The video they put up has been taken down because of claims of 3rd-party content, whatever whatever corporate lawyer stuff internet throttling stuff. That makes me think that Bennetton or one of the others whose stores were glimpsed in the background got their hooks in Vimeo.
So I thought I’d tell you a yarn about how this thing works:
You download the open-source plans for the machine.
You build it.
You download their open-souce clothing-maker program.
You enter the desired measurements into the fields (the ones I remember from the video were arm and neck and chest measurements, so I’m sure they have waist and/or hips too)
You print out your sweater, or hat, or scarf, or cardigan, or whatever it was that you selected. It takes an hour to print out the sweater, working off of the two yarn spools that you can see in the bottom right corner of this .gif
That’s it. Custom-fit, custom-color clothing in an hour, for the price of yarn. Can you see why one of the clothing companies targetted in the video might have felt threatened enough to force the video to come down?

I know if I sold overpriced manufactured clothes, I’d see this as a looming menace.

(via twocrowsfor)

unculture:

street style, Esther Quek, Milan

i am terrified that none of you understand how important esther quek is

(via kiransingh)

variola-vera:

tawghasa:

Adelaide researchers claim a breakthrough in tackling HIV and hepatitis C using a DNA vaccine.

"Because we want to improve the efficacy of the DNA vaccination, we target the skin because the skin has a much greater proportion of white blood cells, which are important for the kind of immunity that we’re trying to impart," he [Adelaide University’s Professor Eric Gowans] said.

The DNA vaccine stimulates the body’s immune response and combines with the white blood cells to kill HIV or hepatitis C cells.

"What we need to do is to target that small population of white blood cells, which circulate generally in the body, and unless the vaccine targets those cells, the vaccine isn’t effective and isn’t efficient in any way," Professor Gowans said.

"So we’ve developed a strategy that targets these white blood cells in an indirect manner; we generate a little inflammation and that attracts all these white blood cells to that site of vaccination."

Professor Gowans says other researchers have used skin to deliver the vaccine, but not to target white blood cells in this way.

"We kill the cells that the vaccine is targeted to, and then those dead cells are highly inflammatory and they attract more of these white blood cells, so that is the difference," he said.

The vaccine is currently designed to treat patients who already have hepatitis C.

The article also adds “… Professor Gowans says it is likely it could be used as a preventative vaccine for hepatitis C and HIV in the next five years" but considering the vaccine is not going into its first clinical trials until next year, I suspect that "five years" is more of a hope than a reality. That said, people have been looking at DNA vaccines for HIV for a long time, and if they’re mainly doing trials to make sure the delivery method works, then perhaps it will be as simple as plugging an existing HIV vaccine into the new delivery method. Anyway, exciting stuff.

Sorry, but that article is completely incomprehensible from an actual virology and immunology stand point. HCV and HIV are completely different viruses, there is literally no vaccine that will induce an adaptive immune response that will protect against both, and an innate immune response is likely to be highly ineffective at either. It is possible that the research is saying he’s found a delivery/adjuvant combo that could potentially increase the immune response to a standard vaccine, but the basis for the vaccine still needs to be virus specific. The problem is there’s no actual scientific paper cited in the article, so there’s no way for me to assess the actual biology behind his claims. Which, again, from a biological stand point are way too vague to be meaningful. Plus, he’s basically saying he induces a non-specific inflammatory immune response, which really isn’t ideal. It’s too broad and can result in really bad secondary effects like cytokine storms. Furthermore, DNA vaccines skin delivery aren’t new, they’ve been around for at least 5 years, so the ‘exciting new’ technology he’s talking about isn’t new.

Plus, there are no effective HIV vaccines, regardless of delivery mechanism. HIV envelope protein is highly glycosylated (covered in sugars) that mask any immune targets and the few exposed regions undergo very high mutation rates, making antibody based immunity very hard to induce (antibody based immunity is how all current vaccines work). Furthermore, even in the cases where people develop broadly neutralizing antibodies, there is little evidence that those antibodies actually protect the people from developing AIDS. A big part of this is that we actually have a very poor understanding of how HIV persists in people. Patients can go on antiretroviral drugs (HAART) and decrease the viral burden (viral infection), but as soon as they stop taking the drugs the virus reemerges and kills their remaining immune cells. So there’s this ‘unknown reservoir’ of quiescent infected cells that maintain the virus even on drug therapy. And we don’t know what they are. Inducing a broad inflammatory immune response is very unlikely to actually affect that population. 

So, that’s kinda long and ramble-y, but it basically boils down to, that article is bullshit. And since they didn’t link to an actual paper, I can’t tell if his claims are bullshit as well. Don’t believe this. At all.

Oh, and I am a virology graduate student at a top 10 virology/microbiology research university. I study the innate immune response to virus infection.

#IAmAnActualScientist #BullshitScience 

Here’s an article on the University of Adelaide site that expalins the mechanism of the vaccine a little more clearly (it’s currently linked on  the home page in a massive way) and here’s an article on pubmed from August 2012 on the same stuff (I assumed everything on pubmed is behind a paywall these days, so the title is “Induction of Multi-Functional T Cells in a Phase I Clinical Trial of Dendritic Cell Immunotherapy in Hepatitis C Virus Infected Individuals (DC Immunotherapy in HCV Infection)”, PLoS One. 2012; 7(8): e39368).

You’re definitely right that the article I linked to is a media splash rather than an academic article. Pros and cons there: news sites break stuff down into easier chunks of information, which is really helpful for people who aren’t experts on a subject. But they also add hype and they get stuff wrong and things can be miscommunicated. Every time someone tells me “They’ve done this new thing in medical research!” I reply “I bet they haven’t,” because you’re right a lot of the stuff that’s reported as being “new” is years old. I think that’s because there’s not really any interest from the general public in this stuff until someone is able to say “This is a thing that works and we have a plan to apply it to that thing you care about!”

I linked to ABC news because their science reporting is better than a lot of outlets, and anyone who wanted to follow the link wouldn’t have to worry about negotiating a paywall to get to an academic paper. I figured that anyone who had enough immuno background to have further questions would be able to look up the research group and their papers themselves. I guess it was laziness on my part - I threw the OP together while drinking my morning coffee at work because it sparked me interest. I could have hunted down the actual research, uploaded the pdfs of articles somewhere and put links so people could read the exciting stuff themselves but, eh. I had DNA extractions to get back to.

(via rrrowr)